ea0037gp.17.03 | Pituitary–Neuroendocrinology and central salt regulation | ECE2015
Sarem Zeinab
, Assefa Biruhalem
, Weickert Martin O
, Adamidou Aikatarini
, Frystyk Jan
, Mohlig Matthias
, Lieske Stefanie
, Birkenfeld Andreas L
, Pfeiffer A.F.H
, Spranger Joachim
, Arafat Ayman M
Background: The mechanisms underlying the association between severe hypoglycaemia and increased cardiovascular mortality among patients with diabetes mellitus are not fully understood. Our aim was to evaluate changes in GH/IGF1 axis during insulin-induced hypoglycaemia, as a possible link.Methods: Twenty-five healthy subjects, 12 obese participants (OP; 6/ 6; 34.4±1.7 kg/m2), and 13 healthy lean participants (LP; 6/ 7; 21.7±0.6 kg/m...